Peptide Nucleic Acids Morpholinos And Related Antisense Biomolecules
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Peptide Nucleic Acids Morpholinos And Related Antisense Biomolecules
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Author : Christopher Janson
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-03-06
Peptide Nucleic Acids Morpholinos And Related Antisense Biomolecules written by Christopher Janson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-06 with Medical categories.
This volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other available oligonucleotide homologues and considers areas in which these biomolecules could be profitably applied to clinical and diagnostic applications. Part I of the book addresses comparative strengths and weaknesses of various nucleoside homologues. Part II of the book addresses specific translational or clinical applications for PNA and related antisense biomolecules. The editors have succeeded in presenting a balanced yet broad view of the methods available for gene targeting and modification.
Peptide Nucleic Acids
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Author : Eylon Yavin
language : en
Publisher:
Release Date : 2020-09-10
Peptide Nucleic Acids written by Eylon Yavin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-10 with categories.
This book compiles four review articles and four research papers that highlight recent developments in the field of peptide nucleic acid (PNA) chemistry and biomedicine. The review articles encompass a variety of fields related to PNA, emphasizing the versatility of this DNA mimic. Two excellent reviews detail the use of PNA for molecular diagnostics of miRNAs and genetic point mutations (SNPs). Another review provides a comprehensive analysis of the various approaches for gene editing using chemically modified PNA molecules. Lastly, PNA molecules are elegantly described as effective (antisense) antimicrobial agents in the final review. The high binding affinity of PNA to complementary DNA and RNA is highlighted in three research articles. Two articles show how PNA molecules act as splice modulating and RNA masking molecules, separately. In another contribution, the high affinity and achiral characteristics of PNAs are used to developed a stable L-DNA-based catalytic hairpin assembly. Lastly, chemically-modified PNA molecules are shown to be superior probes for SNP detection. Altogether, these studies illustrate how PNA molecules may be useful for a variety of biomedical applications as either therapeutic or diagnostic agents.
Morpholino Oligomers
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Author : Hong M. Moulton
language : en
Publisher:
Release Date : 2017
Morpholino Oligomers written by Hong M. Moulton and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Biochemistry categories.
This volume presents a historical perspective on Morpholinos, an overview of good Morpholino practices, techniques for controlling Morpholino activity with light, techniques for modulating microRNA activity in zebrafish embryos, probing genes during fin regeneration, methods for determining to structure of gene networks during development, electroporation, bacterial knockdowns, pretargeting, diagnostic applications of Morpholinos, techniques for delivering Morpholinos in utero to developing embryos, and methods offering rapid, hands-free, label-free and inexpensive assays of Morpholino concentrations in biological extracts. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Morpholino Oligomers: Methods and Protocols aims to provide a diverse application of Morpholinos along with protocols that will assist new labs in moving the frontier.
The British National Bibliography
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Author : Arthur James Wells
language : en
Publisher:
Release Date : 2006
The British National Bibliography written by Arthur James Wells and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Bibliography, National categories.
Therapeutic Oligonucleotides
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Author : Jens Kurreck
language : en
Publisher: Royal Society of Chemistry
Release Date : 2008
Therapeutic Oligonucleotides written by Jens Kurreck and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
This book provides a compelling overall update on current status of RNA interference
Peptide Nucleic Acids
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Author : Peter E. Nielsen
language : en
Publisher: Garland Science
Release Date : 2004
Peptide Nucleic Acids written by Peter E. Nielsen and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Science categories.
Peptide Nucleic Acids, Second Edition has been extensively revised, updated, and enlarged to contain many new chapters covering the most recent topics and applications in this fast-moving field. The book contains state-of-the-art protocols and applications on all aspects of peptide nucleic acids. Concepts are clearly explained with each chapter containing concise background information. Written by leading experts in the field, the book is an invaluable and complete reference work on this novel and exciting area.
Nucleic Acids Conjugates For Biotechnological Applications
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Author : Tamaki Endoh
language : en
Publisher: Mdpi AG
Release Date : 2021-12-06
Nucleic Acids Conjugates For Biotechnological Applications written by Tamaki Endoh and has been published by Mdpi AG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-06 with categories.
Life in biological systems is maintained by the cooperative actions of various biomolecules. With the development of chemical and biological technologies related to nucleic acids, the details of the mechanisms of such cooperative actions between nucleic acids and other biomolecules have been elucidated and further applied in various applications. In the papers published in this Special Issue, advanced research works involved in nucleic acid conjugates are reported in wide application fields, such as artificial gene regulation, biomolecular sensing, and therapeutics from leading scientists in nucleic acids chemistry and engineering.